Human artificial chromosome containing human antibody λ light chain gene and non-human animal containing the human artificial chromosome capable of genetic transmission
Number of patents in Portfolio can not be more than 2000
United States of America Patent
Stats
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Nov 22, 2016
Issued Date -
N/A
app pub date -
Jun 16, 2008
filing date -
May 11, 2001
priority date (Note) -
In Force
status (Latency Note)
Importance
Abstract
The present invention relates to a human artificial chromosome which is genetically transmissible to the next generation with high efficiency and the method for using the same. More specifically, the present invention relates to: a human artificial chromosome in which an about 3.5 Mb to about 1 Mb region containing an antibody λ light chain gene derived from human chromosome 22 is bound to a chromosome fragment which is transmissible to a progeny through a germ line of a non-human animal, said chromosome fragment is derived from another human chromosome; a non-human animal carrying the human artificial chromosome and an offspring thereof; a method for producing the non-human animal; a method for producing a human antibody using the nonhuman animal or an offspring thereof; and a human antibody-producing mouse carrying the human artificial chromosome.
First Claim
Other Claims data not available
Family
International Classification(s)
- 2008 Application Filing Year
- A61K Class
- 9711 Applications Filed
- 5862 Patents Issued To-Date
- 60.37 % Issued To-Date
Cited Art Landscape
Patent Citation Ranking
- 3 Citation Count
- A61K Class
- 38.16 % this patent is cited more than
- 9 Age
Maintenance Fees
| Fee | Large entity fee | small entity fee | micro entity fee | due date |
|---|---|---|---|---|
| 11.5 Year Payment | $7400.00 | $3700.00 | $1850.00 | May 22, 2028 |
