Treatment of fibrosis using FXR ligands

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United States of America Patent

PATENT NO 9498484
SERIAL NO

11081002

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Abstract

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The present invention relates to a method for inhibiting fibrosis that occurs in an organ where the farnesoid X receptor (FXR) is expressed. This method involves the step of administering a high potency, activating ligand of FXR in an effective amount to a patient who is not suffering from a cholestatic condition. The invention also provides pharmaceutical compositions containing an effective amount of an FXR ligand and kits for dispensing the pharmaceutical compositions.

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Patent Owner(s)

Patent OwnerAddress
INTERCEPT PHARMACEUTICALS INC450 W 15TH STREET SUITE 505 NEW YORK NY 10011

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Fiorucci, Stefano Perugia, IT 24 477
Pellicciari, Roberto Perugia, IT 87 958
Pruzanski, Mark New York, US 25 312

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