Human control antibodies and uses therefor
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United States of America Patent
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Nov 15, 2016
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app pub date -
Apr 2, 2013
filing date -
Apr 2, 2012
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Abstract
The present invention provides novel, rationally designed human control antibodies for use in various in vivo and in vitro applications. The antibodies of the present invention have well characterized variable domains that have been designed to minimize or eliminate antigen binding without altering gross antibody structure. Using the antibodies of the present invention in various assays allows researchers to distinguish effects that result from specific antigen-antibody interactions from other, non-specific antibody effects.
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