Methods of using ERBB2 conjugate peptides
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United States of America Patent
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Nov 15, 2016
Grant Date -
Aug 28, 2014
app pub date -
Feb 24, 2014
filing date -
Feb 22, 2013
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Abstract
Compositions that inhibit or block the interaction between Erbin and ErbB2 and methods of their use are provided. Preferred compositions include peptides that inhibit or block Erbin and ErbB2 interaction under physiologic conditions in a subject. One embodiment provides an isolated peptide fragment of ErbB2 including the C-terminal 15 amino acids of ErbB2. The peptide fragment can be about 15 to 27 amino acids in length.
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