Long-acting oxyntomodulin variants and methods of producing same
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United States of America Patent
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Dec 20, 2016
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Mar 12, 2015
app pub date -
Apr 17, 2013
filing date -
Apr 17, 2013
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Abstract
This invention is directed to a chorionic gonadotrophin carboxy terminal peptide (CTP) modified dual GLP-1/glucagon receptor agonist, and methods of producing and using the same. In one embodiment, the present invention provides a CTP-modified polypeptide comprising a dual GLP-1/glucagon receptor agonist and at least one chorionic gonadotrophin carboxy terminal peptide (CTP) attached to the amino terminus or carboxy terminus of the agonist.
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