Triazole macrocycle systems

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United States of America Patent

PATENT NO 9493509
SERIAL NO

14677679

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Abstract

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The present invention provides novel peptidomimetic macrocycles and methods for their preparation and use, as well as amino acid analogs and macrocycle-forming linkers, and kits useful in their production. Macrocycles of the invention include triazole moieties that crosslink amino acid side chains. The cross links can stabilize a secondary structure of a peptidomimetic macrocycle, such as an α-helix.

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Patent Owner(s)

Patent OwnerAddress
AILERON THERAPEUTICS INC490 ARSENAL WAY WATERTOWN MA 02472

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Nash, Huw M Concord, US 72 2496

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  • 16 Citation Count
  • C07C Class
  • 92.22 % this patent is cited more than
  • 9 Age
Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges8711227112381574101 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7001002003004005006007008009001000110012001300

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