Process for the synthesis of 1-(2-((2,4-dimethylphenyl)thio)phenyl)piperazine

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United States of America Patent

PATENT NO 9493409
APP PUB NO 20160060215A1
SERIAL NO

14781716

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Abstract

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The present invention provides new intermediate compounds or formulae (III) and (IVa), and salts thereof, and their use in a new synthetic process for the production of 1-(2-((2,4-dimethylphenyl)thio)phenyl)piperazine (vortioxetine) an experimental drug under development for the treatment of depression and anxiety.

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Patent Owner(s)

Patent OwnerAddress
LEK PHARMACEUTICALS D DSLOVENIA LJUBLJANA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Zupancic, Borut Ljubljana, SI 5 5

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