Efficient dilution method, including washing method for immunoassay
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United States of America Patent
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Nov 15, 2016
Grant Date -
Jul 17, 2014
app pub date -
Jan 16, 2013
filing date -
Jan 16, 2013
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Abstract
A method of droplet manipulation utilizing a droplet manipulation device includes activating elements of the device to bring a first droplet into proximity of a second droplet, controlling the elements of the device to alter the shape of at least one of the first and second droplets, and further controlling the elements of the device to move at least one of the first or second droplets until the droplets are in contact about an aggregate area. The elements are controlled in a manner so as to control the area of contact and the degree of mixing of the fluid between the first and second droplets. The method may be employed to move particles of a particulate suspension from the first droplet to the second droplet. The droplet manipulation device may be an electrowetting on dielectric (EWOD) device, which includes shaping electrodes activated to shape droplets, and a bridging electrode activated to join the droplets to transfer fluid between the shaped droplets.
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