Method for suppressing cell growth

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United States of America Patent

PATENT NO 9492568
APP PUB NO 20110300631A1
SERIAL NO

13132911

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Disclosed is a method for suppressing the growth of a target cell, which is not limited in the type of a target cell and the type of a protein to be expressed in the target cell and needs not any preparatory experiment for determining a codon to be contained in a protein to be expressed in a target cell. Specifically disclosed is a method for suppressing the growth of a target cell, which comprises the steps of: incorporating DNA containing a region encoding a protein into the target cell, and allowing a protein encoded by the DNA to be expressed in the target cell into which the DNA has been incorporated. The region contained in the DNA comprises a tri-nucleotide sequence. The tri-nucleotide sequence is selected from codons that define at least some amino acid species constituting the protein, and is complementary to at least some codons that are used in the target cell at a frequency of 0.2 or less.

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Patent Owner(s)

Patent OwnerAddress
JAPAN AGENCY FOR MARINE-EARTH SCIENCE AND TECHNOLOGYYOKOSUKA-SHI KANAGAWA 237-0061

International Classification(s)

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  • 2009 Application Filing Year
  • A61K Class
  • 10313 Applications Filed
  • 6747 Patents Issued To-Date
  • 65.43 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances200920102011201220132014201520162017201820192020202120222023202420250255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kobayashi, Hideki Yokosuka, JP 316 3367

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Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges6209860894426710349291291182201 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +0500100015002000250030003500400045005000550060006500700075008000850090009500

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11.5 Year Payment $7400.00 $3700.00 $1850.00 May 15, 2028