Engineered cells expressing multiple immunomodulators and uses thereof

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United States of America Patent

PATENT NO 9492482
SERIAL NO

13123129

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Abstract

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This invention relates to the field of therapeutics. Most specifically invention provides methods of generating in vitro engineered immune cells conditionally expressing interleukin-12 (IL-12) and one or more immunomodulators under the control of a gene expression modulation system in the presence of activating ligand and uses for therapeutic purposes in animals.

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Patent Owner(s)

Patent OwnerAddress
INTREXON CORPORATION1872 PRATT DRIVE BLACKSBURG VA 24060

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Beech, Robert P Cincinnati, US 16 74
Reed, Thomas D Arlington, US 49 460

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