Stabilized transglutaminase and process for production thereof
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United States of America Patent
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Nov 8, 2016
Grant Date -
Feb 11, 2016
app pub date -
Oct 27, 2015
filing date -
Feb 13, 2008
priority date (Note) -
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Abstract
Disclosed is a transglutaminase having excellent stability. Also disclosed is a process for producing the transglutaminase. Specifically disclosed is a stabilized transglutaminase, which has such a structure in which a pro-sequence peptide of transglutaminase is bound to a mature transglutaminase. Also specifically disclosed is a process for producing stabilized transglutaminase, which includes the steps of culturing a microorganism capable of producing transglutaminase under the conditions where transglutaminase can be produced; and separating and collecting matured transglutaminase having a pro-sequence peptide bound thereto from a culture medium.
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