Compositions comprising polyglutamic acid nanoparticles and CD40 agonists
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United States of America Patent
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Nov 8, 2016
Grant Date -
Jan 31, 2013
app pub date -
Apr 13, 2011
filing date -
Apr 13, 2010
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Abstract
The present invention provides pharmaceutical compositions comprising an immunostimulatory polypeptide and polyglutamic acid (PGA) nanoparticles, formulated in a pharmaceutically acceptable diluent, carrier or excipient. Such compositions have utility in stimulating the immune system in subjects, with the components capable of interacting synergistically. The invention further provides uses of the compositions of the invention, for example in the treatment of cancer, and kit and components for use in the same.
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