Compositions and methods for the diagnosis and therapy of BCL2-associated cancers

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United States of America Patent

PATENT NO 9480699
APP PUB NO 20140335161A1
SERIAL NO

14341145

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Abstract

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Provided are methods and compositions for the treatment of cancers associated with overexpression of a BCL2 gene and/or gene product in a subject, and methods and compositions for the improvement of anti-cancer therapy, such as chemotherapy and radiation therapy. Also provided are methods for determining the efficacy of a cancer therapy in a subject, methods for diagnosing cancer, methods for assessing patient prognosis, and methods for inducing apoptosis of a cell.

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Patent Owner(s)

Patent OwnerAddress
THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION1314 KINNEAR ROAD COLUMBUS OHIO 43212

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Calin, George A Pearland, US 53 1033
Croce, Carlo M Columbus, US 177 3475

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