Single domain binding molecule

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United States of America Patent

PATENT NO 9475870
SERIAL NO

15005463

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Abstract

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The present invention provides a single domain specific binding molecule having the structure

    FW1-CDR1-FW2-HV2-FW3a-HV4-FW3b-CDR3-FW4in which the Framework Regions FW1, FW2, FW3a, FW3b, and FW4, the Complementarity Determining Regions CDR1 and CDR3, and the Hypervariable Regions HV2, and HV4 have amino acid sequences as defined which provide a high affinity anti-human serum albumin (HSA) binding domain.

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Patent Owner(s)

Patent OwnerAddress
ELASMOGEN LIMITEDLIBERTY BUILDING FORESTERHILL ABERDEEN AB25 2ZP

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Barelle, Caroline Aberdeen, GB 9 17
Bikker, Jack Union Beach, US 9 62
Calabro, Valerie Carro, FR 6 38
Kovalenko, Oleg Cambridge, US 6 16
Muller, Mischa Roland Zurich-Schlieren, CH 4 13
Olland, Andrea Arlington, US 5 15
Steven, John Aberdeen, GB 13 77
Tchistiakova, Lioudmila Cambridge, US 43 970

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