Pyridonaphthyridine type dual PI3K and mTOR inhibitor and its preparation and use

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United States of America Patent

PATENT NO 9475812
APP PUB NO 20140093505A1
SERIAL NO

14123934

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Abstract

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The present invention relates to a pyridonaphthyridine compound as represented by general formula (I), which has a dual PI3K and mTOR inhibition effect, and its pharmaceutically acceptable salt, stereoisomer and deuteride thereof, wherein R1, R2, R3, R4, R5, R6, R7 and X are as defined in the specification; the present invention also relates to a method for preparing said compound, a pharmaceutical composition and a pharmaceutical formulation containing said compound, and uses of said compound in treating and/or preventing a proliferative disease and in the manufacture of a medicament for treating and/or preventing a proliferative disease.

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Patent Owner(s)

Patent OwnerAddress
XUANZHU PHARMA CO LTD2518 TIANCHEN STREET NATIONAL HIGH-TECH DEVELOPMENT ZONE JINAN-CITY SHANDONG PROVINCE 250101

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Wu, Frank Jinan, CN 101 2813
Zhang, Yan Jinan, CN 881 7426

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