Composition for stabilizing fusion protein in which protein and FC domain are fused

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United States of America Patent

PATENT NO 9474803
APP PUB NO 20150313996A1
SERIAL NO

14439644

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Abstract

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The present invention relates to a composition for stabilizing a fusion protein of a physiologically active protein and an Fc domain, and more particularly to a method of stabilizing a fusion protein of a protein and an Fc domain using a composition containing an ammonium salt or a combination of an ammonium salt and succinate. The composition containing an ammonium salt or a combination of an ammonium salt and succinate according to the present invention can effectively inhibit the aggregation of the protein-Fc domain fusion protein, and thus enables the fusion protein to be stored for a long period of time. Accordingly, the composition can be widely used in the medical field that uses the protein-Fc domain fusion protein.

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Patent Owner(s)

Patent OwnerAddress
ALTEOGEN INC62 YUSEONG-DAERO 1628BEON-GIL YUSEONG-GU DAEJEON 34054

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kim, Seong-Kyu Daejeon, KR 5 33
Park, Soon Jae Daejoen, KR 21 105

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