Mesenchymal stem cells for the treatment of CNS diseases
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United States of America Patent
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Oct 25, 2016
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Dec 1, 2014
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May 28, 2008
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Abstract
An isolated human cell is disclosed comprising at least one mesenchymal stem cell phenotype and secreting brain-derived neurotrophic factor (BDNF), wherein a basal secretion of the BDNF is at least five times greater than a basal secretion of the BDNF in a mesenchymal stem cell. Methods of generating same and uses of same are also disclosed.
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