Oligonucleotide analogues having modified intersubunit linkages and/or terminal groups
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United States of America Patent
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Oct 18, 2016
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Jun 6, 2014
filing date -
May 28, 2010
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Abstract
Oligonucleotide analogs comprising modified intersubunit linkages and/or modified 3′ and/or 5′-end groups are provided. The disclosed compounds are useful for the treatment of diseases where inhibition of protein expression or correction of aberrant mRNA splice products produces beneficial therapeutic effects.
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