Naphthylurea derivatives and medical applications thereof

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United States of America Patent

PATENT NO 9469639
SERIAL NO

15024300

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Abstract

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The present invention relates to naphthylurea derivatives. Such substances can significantly inhibit VEGFR2 and PDGFR-β receptor tyrosine kinase phosphorylation at nanomolar concentration levels. It is a novel type of tyrosine kinase inhibitors which can be used in the treatment of tyrosine kinase-mediated diseases or symptoms such as malignancies and ocular diseases accompanied with pathologic neovascularization.

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Patent Owner(s)

  • RADIANT PHARMA & TECH. CO., LTD.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Han, Li Zhenjiang, CN 53 2207
Hu, Yingjian Zhenjiang, CN 1 0
Lu, Hongfei Zhenjiang, CN 5 41
Luo, Zhibin Zhenjiang, CN 2 1
Wang, Yun Zhenjiang, CN 472 7076
Zhang, Yanhong Zhenjiang, CN 18 49

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