Itraconazole formulations
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United States of America Patent
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Oct 18, 2016
Grant Date -
Mar 29, 2012
app pub date -
Sep 22, 2011
filing date -
Sep 24, 2010
priority date (Note) -
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Abstract
Provided herein is a pharmaceutical injectable formulation of itraconazole (10 mg/g) where the formulation comprises a solubilizer, a nonionic surfactant/emulsifier, a co-surfactant and a stabilizer. Further provided is a pharmaceutical formulation of itraconazole, said formulation comprising a solubilizer in a concentration of from about 20% to about 75%, a nonionic surfactant/emulsifier in a concentration of from about 20% to about 50%, a co-surfactant in a concentration from about 10% to about 45% and a stabilizer in a concentration of from about 1% to about 15%.
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