Cysteamine in the treatment of fibrotic disease

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United States of America Patent

PATENT NO 9468612
SERIAL NO

14353273

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Abstract

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Fibrotic diseases are characterized by the replacement of healthy tissue with scar tissue and extracellular matrix in response to tissue damage. Here we describe the reduction of extracellular matrix (ECM) deposition, interstitial fibroblasts, interstitial volume, expression of Collagen I mRNA and protein, expression of profibrotic cytokines and macrophage infiltration by Cysteamine treatment.

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Patent Owner(s)

Patent OwnerAddress
SEATTLE CHILDREN'S HOSPITAL (DBA SEATTLE CHILDREN'S RESEARCH INSTITUTE)1900 NINTH AVENUE SEATTLE WA 98101

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Eddy, Allison A Seattle, US 2 6
Okamura, Daryl M Shoreline, US 2 6

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