Compound having ability to inhibit 11Beta-HSD1 enzyme or pharmaceutically acceptable salt thereof, method for producing same, and pharmaceutical composition containing same as active ingredient

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United States of America Patent

PATENT NO 9464044
APP PUB NO 20150210635A1
SERIAL NO

14409414

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Abstract

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The present invention relates to a novel compound or a pharmaceutically acceptable salt thereof inhibiting 11β-HSD1 enzyme activity, a preparation method of the same, and a pharmaceutical composition comprising the same as an active ingredient. Since the compound of the present invention selectively inhibits the activity of 11β-HSD1 (11β-Hydroxysteroid dehydrogenase type 1), the compound of the invention can be effectively used as a therapeutic agent for the treatment of diseases caused by the over-activation of 11β-HSD1 such as non-insulin dependent type II diabetes, insulin resistance, obesity, lipid disorder, metabolic syndrome, and other diseases or condition mediated by the excessive activity of glucocorticoid.

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Patent Owner(s)

Patent OwnerAddress
INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION119 ACADEMY-RO YEONSU-GU INCHEON 22012
AHN-GOOK PHARMACEUTICAL CO LTDSEOUL CITY KOREA SEOUL
BAMICHEM CO LTDYEONSU-GU INCHEON 406 772

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ahn, Soon Kil Seoul, KR 21 227
Auh, Jin Seoul, KR 7 8
Choi, Nam Song Cheonan-si, KR 7 134
Han, Chang Kyun Seoul, KR 8 8
Han, Cheol Kyu Seoul, KR 9 127
Han, Dong-Oh Anyang-si, KR 2 6
Kim, Tae-Jeong Suwon-si, KR 7 31
Pae, Kamsa Seoul, KR 1 6
Shin, Young June Gimhae-si, KR 5 6

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