Individual 5-fluorouracile dose optimization in folfiri treatment

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United States of America Patent

PATENT NO 9463193
APP PUB NO 20110177092A1
SERIAL NO

13121103

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Abstract

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The present invention belongs to the field of improved personalized medicine. More precisely, the present invention relates to a method for progressively optimizing the 5-FU dose administered by continuous infusion in patients treated by a FOLFIRI regimen or a similar regimen, based on the 5-FU plasmatic concentration measured during the previous 5-FU continuous infusion and on a herein described decision algorithm. The present invention also relates to a method for treating a cancer patient in which the 5-FU dose administered in continuous infusion in each FOLFIRI or similar treatment cycle is optimized using the decision algorithm according to the invention.

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Patent Owner(s)

Patent OwnerAddress
CENTRE REGIONAL DE LUTTE CONTRE LE CANCER D'ANGERS49000 ANGERS
UNIVERSITE D'ANGERS49000 ANGERS

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Boisdron-Celle, Michéle Saint Leger Des Bois, FR 1 2
Gamelin, Erick Bouchemaine, FR 5 10
Morel, Alain Juigne Sur Loire, FR 9 83

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