Companion diagnostic for anti-hyaluronan agent therapy and methods of use thereof
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United States of America Patent
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Oct 4, 2016
Grant Date -
Nov 27, 2014
app pub date -
Aug 14, 2014
filing date -
Oct 24, 2011
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Abstract
Methods and diagnostic agents for identification of subjects for cancer treatment with an anti-hyaluronan agent, such as a hyaluronan-degrading enzyme, are provided. Diagnostic agents for the detection and quantification of hyaluronan in a biological sample and monitoring cancer treatment with an anti-hyaluronan agent, for example a hyaluronan-degrading enzyme, are provided. Combinations and kits for use in practicing the methods also are provided.
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