Von willebrand factor variants having improved factor VIII binding affinity

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United States of America Patent

PATENT NO 9458223
APP PUB NO 20140357564A1
SERIAL NO

14378446

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Abstract

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The present invention relates to a polypeptide comprising a modified von Willebrand Factor (VWF) having a higher Factor VIII binding affinity than non-modified VWF, its pharmaceutical use and method of its preparation.

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Patent Owner(s)

Patent OwnerAddress
CSL BEHRING GMBHMARBURG

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hofmann, Kay Cologne, DE 10 114
Schulte, Stefan Marburg, DE 76 678
Weimer, Thomas Gladenbach, DE 56 657

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