Method for producing intermediates for the production of novel macrocycles that are inhibitors of the proteasomic degradation of p27, such as argyrin and derivatives thereof, and uses of said macrocycles

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United States of America Patent

PATENT NO 9458200
APP PUB NO 20110311564A1
SERIAL NO

13000516

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Abstract

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The present invention relates to the use of particular macrocycles that are inhibitors of the proteasomic degradation of p27, in particular argyrin and derivatives thereof, for a treatment in a variety of conditions, such as the induction of immunotolerance, autoimmune diseases, bacterial infections, and proliferative diseases, such as cancers.

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Patent Owner(s)

Patent OwnerAddress
MEDIZINISCHE HOCHSCHULE HANNOVER30625 HANNOVER

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bülow, Leila Hannover, DE 1 2
Brodmann, Tobias Hannover, DE 3 3
Eggert, Ulrike Hannover, DE 3 8
Frank, Ronald Meine, DE 31 520
Girbig, Anna-Katharina Hannover, DE 1 3
Kalesse, Markus Burgdorf, DE 4 13
Malek, Nisar Hannover, DE 2 3
Rentsch, Andreas Hannover, DE 7 15

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