Cyclic peptide-based NPR-B agonists

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United States of America Patent

PATENT NO 9458198
SERIAL NO

13916019

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Abstract

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Disclosed are cyclic, peptide-based novel compounds having NPR-B agonistic activity. Preferred compounds are cyclic peptides containing conventional or non-conventional L- or D-amino acid residues connected to one another via peptide bonds. In some embodiments, provided herein are a cyclic peptide compound with a ring size that is significantly reduced as compared to known NPR-B agonists, such as CNP.

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Patent Owner(s)

Patent OwnerAddress
TAKEDA PHARMACEUTICAL COMPANY LIMITEDOSAKA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hawlisch, Heiko Berlin, DE 6 17
Hellberg, Mark R Arlington, US 124 1363
Hummel, Gerd Berlin, DE 22 178
Knaute, Tobias Berlin, DE 6 17
Osterkamp, Frank Berlin, DE 31 175
Reimer, Ulf Berlin, DE 17 62
Reineke, Ulrich Berlin, DE 34 219
Richter, Uwe Berlin, DE 36 225
Simon, Bernadett Bonn, DE 6 17
Specker, Edgar Berlin, DE 11 19
Woischnik, Markus Berlin, DE 7 50

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