Coupling compounds of NSAID anti-inflammatory and analgesic drugs and EGFR kinase inhibitors, synthesis methods and applications thereof

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United States of America Patent

PATENT NO 9452220
APP PUB NO 20160175453A1
SERIAL NO

14580509

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Abstract

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The present invention discloses coupling compounds of a structure as shown in Formula I, II or III formed by connecting NSAID anti-inflammatory and analgesic drugs and EGFR inhibitors by ester bonds or pharmaceutically acceptable salts or stereoisomers thereof or prodrug molecules thereof:

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Patent Owner(s)

Patent OwnerAddress
GUANZHOU INSTITUTES OF BIOMEDICINE AND HEALTH CHINESE ACADEMY OF SCIENCES190 KAI YUAN AVENUE SCIENCE PARK GUANGZHOU GUANGDONG 510663

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chen, Panyu Guangdong, CN 1 0
Ding, Ke Guangdong, CN 83 511
Liao, Jinxi Guangdong, CN 1 0
Wang, Yican Guangdong, CN 5 0
Zhang, Yanmei Guangdong, CN 21 80

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