Pharmaceutical compositions comprising silica microspheres
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United States of America Patent
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Sep 27, 2016
Grant Date -
Mar 19, 2015
app pub date -
Nov 24, 2014
filing date -
Apr 14, 2006
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Abstract
A topical composition which includes a silica microspheres and an active ingredient in the amount of 0.01 to 15.0% w/w wherein the active ingredient is selected from adapalene, an antibiotic, tazarotene, tretinoin, a retinoid, or any combination thereof. The topical composition may also include benzoyl peroxide as an active ingredient. The topical compositions provide sustained release of the active ingredient so as to reduce skin irritation.
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