Anti-MCAM antibodies and associated methods of use

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United States of America Patent

PATENT NO 9447190
APP PUB NO 20140227292A1
SERIAL NO

14021777

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Abstract

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Described herein are anti-MCAM antibodies and antigen binding fragments thereof that are capable of inhibiting the interaction between MCAM and its ligand, a protein comprising a laminin α-4 chain. These anti-MCAM antibodies and antigen binding fragments thereof may be useful for, for example, treating inflammatory conditions characterized by the infiltration of MCAM-expressing cells into a site of inflammation in the body.

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Patent Owner(s)

Patent OwnerAddress
PROTHENA BIOSCIENCES LIMITEDADELPHI PLAZA UPPER GEORGE STREET DÚN LAOGHAIRE CO DUBLIN A96 T927 IRELAND

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Baker, Jeanne Redwood City, US 14 78
Flanagan, Kenneth San Francisco, US 18 135
Yednock, Theodore A Forest Knolls, US 27 348

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