3,5-diarylazaindoles as DYRK1A protein inhibitors for the treatment of cognitive deficiencies associated with Down's syndrome and with Alzheimer's disease

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United States of America Patent

PATENT NO 9447093
APP PUB NO 20150307492A1
SERIAL NO

14653570

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Abstract

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The present invention discloses compositions of novel DYRK1A protein inhibitors based on a 3,5-diarylazaindole motif and their preparation and use as medications in the treatment of cognitive disorders associated with dysfunction of DYRK1A protein, with Down's syndrome and with Alzheimer's disease.

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Patent Owner(s)

Patent OwnerAddress
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEPARIS FRA
UNIVERSITE PARIS DIDEROT PARIS 75 RUE THOMAS MANN PARIS F-75013
UNIVERSITE DE REIMS CHAMPAGNE-ARDENNE2 AVENUE ROBERT SCHUMAN REIMS 51100

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cariou, Kevin Paris, FR 3 6
Dairou, Julien Boulogne-Billancourt, FR 1 6
Delabar, Jean Maurice Kremlin Bicetre, FR 1 6
Denhez, Clement Reims, FR 2 6
Dobb, Robert Paris, FR 1 6
Gourdain, Stephanie Gif sur Yvette, FR 1 6
Janel, Nathalie Paris, FR 1 6
Rodrigues, Lima Fernando Saint Maurice, FR 1 6

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