Gas-filled microvesicles with polymer-modified lipids
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United States of America Patent
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Sep 20, 2016
Grant Date -
Oct 22, 2009
app pub date -
Sep 4, 2007
filing date -
Sep 5, 2006
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Abstract
Image enhancing contrast agents for use in diagnostic and/or therapeutic methods, particularly in the form of gas-filled microvesicles, with enhanced stability. The gas-filled microvesicles are stabilized by a layer of amphiphilic material and comprise from 0.15% to 1.0% by moles of a lipid bearing a hydrophilic polymer. The lipid bearing a hydrophilic polymer is preferably a phospholipid linked to polyethyleneglycol.
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