Glypican-4 based compositions and methods for treating and diagnosing insulin resistance
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United States of America Patent
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Sep 20, 2016
Grant Date -
Dec 11, 2014
app pub date -
Dec 31, 2012
filing date -
Dec 30, 2011
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Abstract
Provided herein are methods for increasing insulin sensitivity in a subject. A method may comprise administering to a subject in need of increased insulin sensitivity a therapeutically effective amount of a glypican-4 agent. Also provided herein are methods for determining whether a subject is or is likely to become insulin resistant. A method may comprise determining the level of glypican-4 in a subject, wherein an elevated level of glypican-4 indicates that a subject is or is likely to become insulin resistant.
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