Enzyme immobilization by crosslinking

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United States of America Patent

PATENT NO 9441258
APP PUB NO 20150001074A1
SERIAL NO

13930890

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Abstract

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An analyte sensor for the continuous or semi-continuous monitoring of physiological parameters and a method for making the analyte sensor are disclosed. In one aspect, the analyte sensor includes an electrode, a sensing layer in contact with a surface of the electrode, and a protective membrane. The sensing layer is a crosslinked, hydrophilic copolymer including poly(alkylene oxide) and poly(vinyl pyridine), and an analyte sensing component is immobilized within the crosslinked, hydrophilic copolymer. The protective membrane is a crosslinked, hydrophilic copolymer including alkylene oxide, vinyl pyridine and styrene units. The method involves the formation of a sensing layer on a surface of an electrode, followed by the formation of a protective membrane on a surface of the sensing layer.

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Patent Owner(s)

Patent OwnerAddress
GOOGLE LLC1600 AMPHITHEATRE PARKWAY MOUNTAIN VIEW CA 94043

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Liu, Zenghe Mountain View, US 130 5363

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