Manipulation of fluids and reactions in microfluidic systems

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United States of America Patent

PATENT NO 9440232
APP PUB NO 20150118761A1
SERIAL NO

14577652

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Microfluidic structures and methods for manipulating fluids and reactions are provided. Such structures and methods may involve positioning fluid samples, e.g., in the form of droplets, in a carrier fluid (e.g., an oil, which may be immiscible with the fluid sample) in predetermined regions in a microfluidic network. In some embodiments, positioning of the droplets can take place in the order in which they are introduced into the microfluidic network (e.g., sequentially) without significant physical contact between the droplets. Because of the little or no contact between the droplets, there may be little or no coalescence between the droplets. Accordingly, in some such embodiments, surfactants are not required in either the fluid sample or the carrier fluid to prevent coalescence of the droplets. Structures and methods described herein also enable droplets to be removed sequentially from the predetermined regions.

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Patent Owner(s)

Patent OwnerAddress
BRANDEIS UNIVERSITY415 SOUTH STREET MS 115 WALTHAM MA 02453

International Classification(s)

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  • 2014 Application Filing Year
  • G01N Class
  • 10055 Applications Filed
  • 7887 Patents Issued To-Date
  • 78.44 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances2014201520162017201820192020202120222023202420250255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cristobal-Azkarate, Galder Bordeaux, FR 14 938
Fraden, Seth Newton, US 26 664

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Patent Citation Ranking

  • 1 Citation Count
  • G01N Class
  • 31.44 % this patent is cited more than
  • 9 Age
Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges232940745921838355241515882101 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +0250500750100012501500175020002250250027503000325035003750400042504500

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