Biocompatible phase invertible proteinaceous compositions and methods for making and using the same

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United States of America Patent

PATENT NO 9440000
SERIAL NO

14178093

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Abstract

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Biocompatible phase invertible proteinaceous compositions and methods for making and using the same are provided. The subject phase invertible compositions are prepared by combining a crosslinker and a proteinaceous substrate. The proteinaceous substrate includes one or more proteins and a polyamine, where the polyamine and a proteinaceous substrate are present in synergistic viscosity enhancing amounts, and may also include one or more of: a carbohydrate, a tackifying agent, a plasticizer, or other modification agent. In certain embodiments, the crosslinker is a heat-treated dialdehyde, e.g., heat-treated glutaraldehyde. Also provided are kits for use in preparing the subject compositions. The subject compositions, kits and systems find use in a variety of different applications.

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Patent Owner(s)

Patent OwnerAddress
BAXTER INTERNATIONAL INCONE BAXTER PARKWAY DEERFIELD IL 60015

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Handley, Ian J Mountain View, US 10 24
Wong, Joanna Santa Clara, US 13 27

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