Tat DNA sequences, gene constructs, vaccine and processes thereof

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United States of America Patent

PATENT NO 9439922
APP PUB NO 20110165191A1
SERIAL NO

12988341

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Abstract

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The present invention relates to non toxic, immunogenic viral Tat DNA sequences comprising wherein the Tat Sequence is rendered non toxic and immunogenic by insertion of T-Helper Epitope into the Cysteine-rich domain, or Basic domain or Core domain of said Tat DNA sequence, optionally along with insertion of a synthetic Intron between C-terminal region and Exon II region of the Tat DNA Sequence. The present invention also relates to elongation factor promoter constructs and process thereof. Also the present invention relates to a process of obtaining the non toxic and immunogenic Tat DNA sequence and vaccine and a method thereof.

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Patent Owner(s)

Patent OwnerAddress
JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCHJAKKUR KARNATAKA BANGALORE 560064

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ranga, Udaykumar Karnataka, IN 2 3

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