Cancer therapy using a combination of HSP90 inhibitors with topoisomerase I inhibitors
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United States of America Patent
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Sep 13, 2016
Grant Date -
Sep 11, 2014
app pub date -
Nov 1, 2012
filing date -
Nov 2, 2011
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Abstract
A pharmaceutical combination comprising a topoisomerase I inhibitor, and an Hsp90 inhibitor according to the following formulae (I) (Ia) a tautomer, or a pharmaceutically acceptable salt thereof, wherein the variables in the structural formulae are defined herein. Also provided is a method for treating a proliferative disorder in a subject in need thereof, using the pharmaceutical combination described herein.
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