System for non-invasive classification of different types of micro-calcifications in human tissue

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United States of America Patent

PATENT NO 9439615
APP PUB NO 20150030123A1
SERIAL NO

14380817

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Abstract

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A non-invasive method distinguishes between two types of micro-calcification by x-ray imaging in mammography. Two major types of micro-calcifications are found and confirmed by histopathology and they are correlated to benign and malignant breast lesions. Distinguishing between them non-invasively will significantly improve early breast cancer diagnosis. This is based on the fact that these two types of micro-calcifications show opposite absorption and small-angle scattering signals in x-ray imaging. The imaging system, which can record these two signals of the breast tissue simultaneously for instance, an x-ray grating interferometer, can be used to uniquely determine the micro-calcification type. This is expected to be used in mammography to improve early breast cancer diagnosis, increase diagnosis accuracy and decrease the biopsy rate.

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Patent Owner(s)

Patent OwnerAddress
PAUL SCHERRER INSTITUTSWITZERLAND ZUG ZUG

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Stampanoni, Marco Endingen, CH 11 166
Wang, Zhentian Brugg, CH 8 88

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