HPMA—docetaxel conjugates and uses therefore

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United States of America Patent

PATENT NO 9434610
APP PUB NO 20100099644A1
SERIAL NO

12575276

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Abstract

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Disclosed are water-soluble compositions of gemcitabine and docetaxel formed by conjugating the gemcitabine or docetaxel to a water-soluble polymer such as N-2-hydroxypropyl methacrylamide (HPMA). Also disclosed are methods of using the compositions of the invention for the treatment of cancer.

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Patent Owner(s)

Patent OwnerAddress
REXAHN PHARMACEUTICALS INC15245 SHADY GROVE ROAD SUITE 455 ROCKVILLE MD 20850
UNIVERSITY OF MARYLAND BALTIMORE620 WEST LEXINGTON STREET 4TH FLOOR OFFICE OF TECHNOLOGY TRANSFER BALTIMORE MD 21201

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ahn, Chang H Potomac, US 11 45
Ghandehari, Hamidreza Salt Lake City, US 14 105
Kim, Deog J Rockville, US 8 21
Lee, Young B Clarksburg, US 12 28
Nan, Anjan Hanover, US 3 52
Ray, Abhijit Salt Lake City, US 71 415

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