Over-production of secondary metabolites by over-expression of the VEA gene
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United States of America Patent
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Aug 30, 2016
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app pub date -
Sep 15, 2014
filing date -
Apr 24, 2009
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Abstract
The invention provides a general and facile method to obtain secondary metabolites from fungal sources. The invention is based on the discovery that the fungal gene veA and protein encoded thereby regulates the activity of multiple secondary metabolite gene clusters in fungi. Over expression of the gene veA provides increased production of secondary metabolites in engineered cells. In particular, such a method of increasing secondary metabolite production allows the production of improved yields of valuable secondary metabolite products.
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- A61K:PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOS....
- C12R:INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C-C1....
- C12Q:MEASURING OR TESTING PROCESSES INVOLVING ENZYMES O....
- C12P:FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESI....
- C12N:MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF
- A01H:NEW PLANTS OR PROCESSES FOR OBTAINING THEM; PLANT ....
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