Method for determining amounts of polynucleotide sequences present in cell or tissue samples
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United States of America Patent
Stats
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Aug 16, 2016
Grant Date -
Mar 18, 2004
app pub date -
Jan 10, 2002
filing date -
Jan 10, 2001
priority date (Note) -
In Force
status (Latency Note)
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Abstract
The invention is related to a method and test kits for quantitative determination of polynucleotide amounts present in a sample. The test kit comprises organized pools with polynucleotide probes having distinct sizes and optionally provided with tracer tags or primer tags. The probes are allowed to hybridize with affinity tagged analyte polynucleotides from the sample. The result is hybrids, which can be recovered on a separation aiding tool provided with the pair of the affinity tag. After the quantitative release of the probes, the probes are either directly recorded, or if primer tagged, they are amplified and optionally provided with a tracer tag before recording. The invention provides a sensitive and quantitative determination of the amount polynucleotides present in a cell or tissue sample and allows a quantitative assessment of variations in the amounts of polynucleotides as a response to inherent changes or due to external stimuli.
First Claim
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International Classification(s)
- 2002 Application Filing Year
- C07H Class
- 2961 Applications Filed
- 539 Patents Issued To-Date
- 18.21 % Issued To-Date
Cited Art Landscape
Patent Citation Ranking
- 0 Citation Count
- C07H Class
- 0 % this patent is cited more than
- 9 Age
Maintenance Fees
| Fee | Large entity fee | small entity fee | micro entity fee | due date |
|---|---|---|---|---|
| 11.5 Year Payment | $7400.00 | $3700.00 | $1850.00 | Feb 16, 2028 |
