Process for preparation of 3-((2s,5s)-4-methylene-5-(3-oxopropyl)tetrahydrofuran-2-yl)propanol derivatives and intermediates useful thereof

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United States of America Patent

PATENT NO 9416140
APP PUB NO 20160031900A1
SERIAL NO

14882845

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Abstract

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Discloses is a process for preparation of a compound of formula 7, or a derivative thereof, wherein PG1 is an alcohol protecting group. Also, disclosed are intermediates and processes for their preparation. The compound of formula 7 can be useful in the preparation of halinchondrin analogs such as Eribulin.

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Patent Owner(s)

Patent OwnerAddress
ALPHORA RESEARCH INC2395 SPEAKMAN DRIVE SUITE 2001 MISSISSAUGA ONTARIO L5K 1B3

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bexrud, Jason A Toronto, CA 5 42
Gorin, Boris Oakville, CA 39 232
Orprecio, Ricardo Mississauga, CA 7 51
Souza, Fabio E S Mississauga, CA 37 36

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