Substituted imidazo[1,2-b]pyridazines as protein kinase inhibitors
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United States of America Patent
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Aug 16, 2016
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Nov 6, 2014
app pub date -
Jul 20, 2012
filing date -
Jul 21, 2011
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Abstract
The present invention provides protein kinase having one of the following structures (I), (II) or (III): or a stereoisomer, prodrug, tautomer or pharmaceutically acceptable salt thereof, wherein R, R1, R2 and X are as defined herein. Compositions and methods for using the same in the treatment of cancer, autoimmune, inflammatory and other Pim kinase-associated conditions are also disclosed.
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