Use of microrna molecules to influence skin pigmentation

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 9410152
APP PUB NO 20150010485A1
SERIAL NO

14366767

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Abstract

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At least one microRNA selected from among hsa-miR-330, hsa-miR-7 and hsa-miR-137, the mature forms thereof, and the precursors thereof, for depigmenting the skin, and an in vitro method for identifying depigmenting compounds, which includes the steps of: a) placing at least one test compound in contact with a sample of melanocytes; b) measuring the expression or activity of at least one microRNA selected from among miR-330, miR-7 and miR-137, the mature forms thereof, and the precursors thereof, in the melanocytes; c) selecting the compounds for which at least 20% activation of the expression or of the activity of at least one of the microRNAs is measured in the melanocytes treated in a) by an element for comparing with the untreated melanocytes.

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Patent Owner(s)

Patent OwnerAddress
INSTITUT CURIE26 RUE D’ULM PARIS 75005
CHANEL PARFUMS BEAUTE135 AVENUE CHARLES DE GAULLE 92200 NEUILLY-SUR-SEINE 92200
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS3 RUE MICHEL ANGE PARIS 75016
INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)101 RUE DE TOLBIAC PARIS 75013

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Larue, Lionel Bures sur Yvette, FR 3 0
Mahe, Christian Neuilly sur Seine, FR 14 93
Rambow, Florian Antony, FR 4 5
Saintigny, Gaelle Paris, FR 18 28

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