Process for the synthesis of carbonucleoside and intermediates for use therein
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United States of America Patent
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Aug 2, 2016
Grant Date -
Jun 6, 2013
app pub date -
May 30, 2011
filing date -
May 31, 2010
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Abstract
Disclosed is a process for preparing a carbonucleoside of formula (1) and intermediates for use therein. The process involves the step of reacting a compound of formula (2) with a compound of formula (3) under Mitsunobu-type reaction conditions to obtain a compound of formula (4), wherein PG1, PG2, PG3 and PG4 are protecting groups. The compound of formula (4) is deprotected to form the compound of formula (1), as shown below.
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