Crystalline form of a quinolinone-carboxamide compound

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United States of America Patent

PATENT NO 9402840
APP PUB NO 20160095849A1
SERIAL NO

14816237

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Abstract

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The invention provides a crystalline hydrochloride salt of 1-isopropyl-2-oxo-1,2-dihydroquinoline-3-carboxylic acid {(1S,3R,5R)-8-[(R)-2-hydroxy-3-(methanesulfonyl-methyl-amino)propyl]-8-azabicyclo[3.2.1]oct-3-yl}amide or a solvate thereof. The invention also provides pharmaceutical compositions comprising such crystalline salt forms, methods of using such crystalline salt forms to treat diseases associated with 5-HT4 receptor activity, and processes useful for preparing such crystalline salt forms.

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Patent Owner(s)

Patent OwnerAddress
ALFASIGMA S P A40133 BOLOGNA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chao, Robert S Santa Clara, US 30 330
Fatheree, Paul R San Francisco, US 143 1473
Genov, Daniel Boston, US 14 103
Goldblum, Adam A Berkeley, US 32 239
Turner, S Derek Reston, US 43 528

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