Combination therapy of HSP90 inhibitors with BRAF inhibitors
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United States of America Patent
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Aug 2, 2016
Grant Date -
Sep 11, 2014
app pub date -
Nov 14, 2012
filing date -
Nov 14, 2011
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Abstract
A pharmaceutical combination comprising a BRAF inhibitor, and an Hsp90 inhibitor according to the following formulae (I): or a tautomer, or a pharmaceutically acceptable salt thereof, wherein the variables are defined therein. Also provided is a method for treating a proliferative disorder in a subject in need thereof, using the pharmaceutical combination described herein.
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