Polyphenol proteasome inhibitors, synthesis, and methods of use

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United States of America Patent

PATENT NO 9399631
APP PUB NO 20140045931A1
SERIAL NO

14057956

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Abstract

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The present invention relates to synthetic green tea derived polyphenolic compounds, their modes of syntheses, and their use in inhibiting proteasomal activity and in treating cancers. The present invention is also directed to pharmaceutical compositions useful in methods of inhibiting proteasomes and of treating cancers.

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Patent Owner(s)

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UNIVERSITY OF SOUTH FLORIDATAMPA FL

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chan, Tak-Hang Montreal, CA 28 66
Dou, Q Ping Grosse Pointe, US 10 64
Smith, David M Boston, US 120 2587

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