Transgenic animal model of mood disorders

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United States of America Patent

PATENT NO 9398761
SERIAL NO

14386319

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Abstract

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A non-human transgenic animal having a polynucleotide encoding a PTN polypeptide, which polynucleotide is operably linked to a promoter, wherein said transgenic animal has greater than wild-type expression of the PTN polypeptide in at least one brain region, as well as related vectors, methods of producing transgenic animals, in vitro and in vivo screening methods for potential therapeutic agents, and methods for treating and diagnosing neuropsychiatric illnesses, particularly anxiety and depression, are disclosed.

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Patent Owner(s)

Patent OwnerAddress
UNIVERSIDAD DEL PAÍS VASCO/EUSKAL HERRIKO UNIBERTSITATEA48940 LEIOA VIZCAYA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Arteta, David Derio, ES 4 1
Ferrer, Marcelo Derio, ES 2 0
Martinez, Antonio Derio, ES 35 350
Simon, Laureano Derio, ES 13 24
Uribarri, Maria Derio, ES 2 0

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